Hello,
In order to try to overcome the experienced problematic behavior, I would suggest you to enable the CDN of the RadScriptManager. In addition, please consider setting the CdnSettings-BaseUrl pointing to the secure address (HTTPS) as demonstrated in the following documentation article:
http://docs.telerik.com/devtools/aspnet-ajax/controls/scriptmanager/cdn-support/custom-cdn-provider
Regards,Nencho
Telerik
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